Priority from the Bleeding Disorders PSP

UNCERTAINTY:  What overall (total) level of coagulation activity do you need to prevent bleeding and how can this be measured? 
Overall ranking This was one of the 15 questions at the workshop that fell outside of the Top 10. These were not ranked in any order of priority
JLA question ID 0078/25
Explanatory note The relationship between individual and multiple coagulation factor levels in the blood is not understood. Yet understanding this is essential for treatment. 
Evidence No systematic reviews
Health Research Classification System category Blood
Extra information provided by this PSP
Original uncertainty examples Not available
Submitted by Not available
PSP information
PSP unique ID 0078
PSP name Bleeding Disorders
Total number of uncertainties identified by this PSP. 66 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 7 July 2018