Priority 8 from the Psoriasis PSP

UNCERTAINTY: To what extent is psoriasis caused by a person’s genes or other factors, such as stress, gut health, water quality, change in the weather or temperature?  (JLA PSP Priority 8)
Overall ranking 8
JLA question ID 0072/8
Explanatory note Not available for this PSP

Albert 2014 Evidence that an exacerbation of psoriasis is frequently associated with lithium treatment.  More studies needed. 

Brenaut, 2013 Evidence that alcohol consumption is greater in psoriasis patients than in the general population.  However, there is not enough evidence to establish whether alcohol consumption is a risk factor for psoriasis.  More research needed. 

Al-Dhubaibi, 2018 Evidence that there is a correlation between psoriasis and Vitamin D deficiency.  There is a need for larger scale case-control studies to assess the role of vitamin D deficiency in psoriasis. 

Please see the data sheet for the further list of evidence considered.

Health Research Classification System category Skin
Extra information provided by this PSP
Original uncertainty examples Does stress aggravate psoriasis and if so to what degree?
Submitted by 252 uncertainties were submitted around this question
PSP information
PSP unique ID 0072
PSP name Psoriasis
Total number of uncertainties identified by this PSP. 55  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 17 September 2018