Priority 10 from the Mesothelioma PSP
|UNCERTAINTY: What, if any, are the benefits of pleurectomy (pleurectomy/decortication) compared to no surgery, and which mesothelioma patients might benefit? (JLA PSP Priority 10)
|JLA question ID
|Not available for this PSP
|Systematic review - Sestini S, Billè A, Okiror L, Gisabella M, Pastorino U. Systematic review on pleurectomy/decortication in the multimodality treatment of malignant pleural mesothelioma. Sestini S et al. Lung Cancer Management Vol. 3, No. 4, Pages 345-354 , DOI 10.2217/lmt.14.26. Ongoing study - MARS 2: A Feasibility Study Comparing (Extended) Pleurectomy Decortication Versus no Pleurectomy Decortication in Patients With Malignant Pleural Mesothelioma
|Health Research Classification System category
|Extra information provided by this PSP
|Original uncertainty examples
|Is there any indication of the efficiency of pleural decortication according to the stage of tumor at the time it is carried out? ~ Further studies are needed to find out whether Pleurectomy surgery is beneficial or not. ~ I also talked to people who have had operations to scrape the lung lining which has been successful is there any criteria for either of these treatments?
|Patient ~ Bereaved ~ Patient
|Outcomes to be measured
|PSP unique ID
|Total number of uncertainties identified by this PSP.
|53 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
|Date of priority setting workshop
|16 December 2014