Priority 14 from the Blood Pressure in Pregnancy PSP

UNCERTAINTY:Is there a hereditary link in pre-eclampsia and are the risks different for daughters and sons after an affected pregnancy?  (JLA PSP Priority 14)
Overall ranking 14
JLA question ID 0099/14
Explanatory note Not available for this PSP
Evidence

None identified
Health Research Classification System category  Reproductive health and childbirth
Extra information provided by this PSP
Original uncertainty examples The genetic factor of pre-eclampsia- how risk can be effectively measured for my daughter for example. ~ Will this mean that my daughter would be at risk if she were to have children I had HELLP and as a result my son died. I went on to have two healthy daughters.  I'm worried about their pregnancies. Have things changed? ~ Will my daughters be more prone to pre-eclampsia it high blood pressure in their pregnancies? ~ genetic  is this a factor   ethnic origin  age ~ Is it a genetic thing ~ Is it hereditary? ~ Moving down maternal side of family...my granny,my mum me but not my sister but will my daughter have the gene for it? ~ Does it follow preeclamptic to preclamptic. 
Submitted by  21 women, 2 researcher, 2 other
PSP information
PSP unique ID 0099
PSP name Blood Pressure in Pregnancy
Total number of uncertainties identified by this PSP.

50 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 20 June 2019