Non Surgical Priority 1 from the Early Hip and Knee Osteoarthritis PSP


UNCERTAINTY: Is regular exercise and physical activity effective at reducing disease progression? (JLA PSP Non Surgical Priority 1)
Overall ranking amongst non surgical questions 1
JLA question ID 0041/11
Extra explanatory note Very real dilemma for many with early OA with differing advice received from health professionals.
Intervention; cardiovascular exercise and specific joint exercise
Type of research; start off with systematic review (Cochrane review is for hip only at present) study needs to be longer term to capture disease progression, cohort and there is a registry of people with OA (non replacement) that could be used?
Population; all people with early OA
Outcomes; difficult to measure disease progression? Important to measure harms
Evidence None identified
Health Research Classification System category Musculoskeletal
Extra information provided by this PSP
Original uncertainty examples Do impact sports, such as running, really lead to knee osteoarthritis?  ~  Does excessive sport (daily for 4 hours) during adolescence make me more likely to develope OA?  ~  Does jogging cause osteoarthritis?
Submitted by 6 patient/carers,11 clinicians and 1 carer/clinician
PSP information
PSP unique ID 0041
PSP name Early Hip and Knee Osteoarthritis
Total number of uncertainties identified by this PSP. 52  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 26 February 2016