Chronic Endometritis and Recurrent Miscarriage - The CERM trial

Addressing priority 1: NIHR research in progress

An antibiotic called doxycycline is commonly used to treat endometritis. This treatment is available at private clinics and in some European countries but this has not been thoroughly tested. To find out if doxycycline can reduce miscarriage and increase the number of births in women who have experienced two or more early miscarriages, this research team will compare a 14-day course of doxycycline against a placebo.

HELP Infertility? (Hysteroscopic Excision of Leiomyoma and Polyp in Infertility): two randomised controlled trials

Addressing priority 1: NIHR research in progress

This study aims to find out if having hysteroscopic removal of fibroids and polyps increases the live birth rate in women with infertility and recurrent miscarriage.