Priority 19 from the Scoliosis PSP

UNCERTAINTY: How is scoliosis linked to other conditions (e.g. osteoporosis, connective tissue disorders, arthritis)? What impact do those conditions have on progression and vice versa? What are the implications for treatment and screening?  (JLA PSP Priority 19)
Overall ranking 19
JLA question ID 0059/19
Explanatory note Not available for this PSP

Previous related research studies - 

None identified

Health Research Classification System category Musculoskeletal
Extra information provided by this PSP
Original uncertainty examples In children with neurodisability, does osteopenia/osteoporosis play a role in the development of scoliosis and subsequently does it effect morbidity/sequelae during the process of surgical internal fixation in the short and long term? ~ What is the relationship between scoliosis and osteoporosis? Should there be a different threshold for osteoporosis treatment in someone with scoliosis?  ~ Is there a link between Scoliosis and hypermobility (so-called double jointed people)? ~ Is there any link between scoliosis and other conditions such as costochondritis, depression or cancers related to exposure to radiation during repeated X-Rays?
PSP information
PSP unique ID 0059
PSP name Scoliosis
Total number of uncertainties identified by this PSP. 54  (To see a full list of all uncertainties identified, please see the PSP final report held on the JLA website)
Date of priority setting workshop 4 November 2017