Priority 5 from the Psoriatic Arthritis PSP

UNCERTAINTY: Does treating psoriatic arthritis early (or proactively) reduce the severity of the disease and/or make it more likely to go into remission? (JLA PSP Priority 5)
Overall ranking 5
JLA question ID 0108/5
Explanatory note This question explores the role of treating psoriatic arthritis early and whether early treatment could help reduce the disease severity or make achieving remission more likely. If this could be answered, it would allow healthcare professionals to tailor treatment more effectively and avoid the risk of over treating some people. For example, which people would benefit from early biological therapy? Does early, aggressive treatment of psoriatic arthritis prevent long-term joint damage? Does early intervention improve the outcome for milder disease? 

This is an area of uncertainty. No systematic reviews or guidelines identified.

Health Research Classification System category Inflammatory and immune system
Extra information provided by this PSP
Original uncertainty examples Which patients will benefit from biological therapy early.  
Submitted by 10 uncertainties submitted 
PSP information
PSP unique ID 0108
PSP name Psoriatic Arthritis
Total number of uncertainties identified by this PSP. 46  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 12 July 2021