Priority 7 from the Obstructive Sleep Apnea (Saskatchewan,Canada) PSP

UNCERTAINTY: Are there other therapies that could be used along with Continuous Positive Airway Pressure (CPAP) to improve obstructive sleep apnea (OSA) and under what circumstances?  (JLA PSP Priority 7)
Overall ranking 7
JLA question ID 0118/7
Explanatory note While Continuous Positive Airway Pressure is the most effective therapy of Obstructive Sleep Apnea, there may be a role for a range of alternative treatments such as weight loss, oral appliances, positional devices, surgery and emerging therapies such as medications.Tailoring therapies to individual needs has become increasing important to improve adherence. 

Randerath WJ, Verbraecken J, Andreas S, Bettega G, Boudewyns A, Hamans E, Jalbert F, Paoli JR, Sanner B, Smith I, Stuck BA, Lacassagne L, Marklund M, Maurer JT, Pepin JL, Valipour A, Verse T, Fietze I; European Respiratory Society
task force on non-CPAP therapies in sleep apnoea. Non-CPAP therapies in obstructive sleep apnoea. Eur Respir J. 2011 May;37(5):1000-28. doi:10.1183/09031936.00099710. Epub 2011 Mar 15. PMID: 21406515. 

Health Research Classification System category Respiratory
Extra information provided by this PSP
Original uncertainty examples I am currently using a cpap machine and still finding that I am tired and don’t get a good sleep at night, is there any other treatments to use in conjunction with the cpap machine treatment? ~ Are the adjuncts with CPAP (example: a-flex/c-flex/EPR) useful in the treatment and compliance with therapy? 
Submitted by Clinicians x 2, patient x 1
PSP information
PSP unique ID 0118
PSP name Obstructive Sleep Apnea PSP
Total number of uncertainties identified by this PSP. 39  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 28 January 2021