Priority 14 from the Myeloma (Canada) PSP

UNCERTAINTY: How can we restore myeloma patients' immune functioning (e.g., IgG treatment) so that they might resume their daily activities (e.g., travel, work) without fear of infections?  (JLA PSP Priority 14)
Overall ranking 14
JLA question ID 0113/14
Explanatory note Participants worried about the effects of myeloma treatment on patients' immune system and the resulting impact on their daily activities including working, socializing, and travelling. Some expressed a fear of infection and wanted more information on the use of IgG treatment, mask wearing, and vaccinations, as well as new treatments that do not supress the immune system.  
Evidence

No evidence identified 
Health Research Classification System category Cancer and neoplasms
Extra information provided by this PSP
Original uncertainty examples How can you disable the immune system with the drugs that slow the growth of this cancer  (such as revlimid) and expect the body to be able to regenerate. ~ I worry about my future with myeloma  and about where I should be going to interact with others in case of infections etc. Research on this would be good. ~ Building their Immune system the giving of a more quality of life without loss of appetite, diarrhea ~ More focus on immune system re-programming to do it's compete job which was compromised with the initial onslaught of the disease? ~ Feeling that the immune system is back to normal (not just the cancer numbers) so the it permits you to live a normal active life again (e.g. travel and contact with public) without always worrying about risks. 
Submitted by  Please see the PSP Engagement Summary on the JLA website 
PSP information
PSP unique ID 0113
PSP name Myeloma (Canada)
Total number of uncertainties identified by this PSP. 59  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 28 April 2021