Priority 10 from the Multiple Sclerosis PSP

UNCERTAINTY: Is physiotherapy effective in reducing disability in people with multiple sclerosis? (JLA PSP Priority 10)
Overall ranking 10
JLA question ID 0016/10
Explanatory note Reliable up-to-date systematic reviews have revealed important continuing uncertainties about treatment effects

Amatya B, Khan F, La Mantia L, Demetrios M, Wade DT. Non pharmacological interventions for spasticity in multiple sclerosis. Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD009974. DOI: 10.1002/14651858.CD009974.pub2.

Systematic reviews that need extending or updating

No reviews found

Systematic reviews in preparation

No reviews found

Ongoing controlled trials

A trial to compare the effectiveness of two rehabilitation programs for Multiple Sclerosis patients REHABMUSCLE NCT01871818

Home Exercise Intervention in persons with Multiple Sclerosis HOMS NCT01824550

Promoting Physical Activity behavior in persons with Multiple Sclerosis NCT01572207

Health Research Classification System category Neurological
Extra information provided by this PSP
Original uncertainty examples No examples provided.  This is an indicative uncertainty and several submissions were merged to form this one. 
Submitted by 3 patients ~ 1 carer ~ 4 clinicians
Outcomes to be measured Management and or change of multiple sclerosis symptoms; adverse effects or complications; acceptability to patients or carers; time to return to work or normal activity; time in hospital and or needing health or social care services; health related quality of life; and costs.
PSP information
PSP unique ID 0016
PSP name Multiple Sclerosis
Total number of uncertainties identified by this PSP. 82  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop July 2013