Priority 13 from the Mitochondrial Disease PSP

UNCERTAINTY: What can prevent mitochondrial disease from getting worse over time? (JLA PSP Priority 13)
Overall ranking 13
JLA question ID 0095/13
Explanatory note  Not available

None identified

Health Research Classification System category Metabolic and Endocrine
Extra information provided by this PSP
Original uncertainty examples treatments to prevent progression/ 2nd eye involvement. ~ Progression as it's the most under researched ~ What is the role of exercise in preventing decline in vision in patients affected by vision loss with LHON? ~ What speeds up or slows down progression  ~ Can adult onset MiTo disease (after some progression) improve and symptoms disappear with good management and care? ~ What can We do to slow progression ~ Anything to limit the condition or improve any longevity would be of interest ~ Also how it has progressed and whether anything can be done to slow progression.
Submitted by 14 x Carers, 7 x Healthcare Professionals, 7 x Patients
PSP information
PSP unique ID 0095
PSP name Mitochondrial Disease
Total number of uncertainties identified by this PSP. 42  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 19 January 2020