Priority 1 from the mitochondrial disease PSP

UNCERTAINTY: Could an understanding of the cellular and molecular processes in mitochondrial disease lead to new treatments? (JLA PSP Priority 1)
Overall ranking 1
JLA question ID 0095/1
Explanatory note Not available 

Health Research Classification System category
Metabolic and Endocrine
Extra information provided by this PSP
Original uncertainty examples Can we develop new drugs that target fundamental defects across a range of mitochondrial diseases?  ~  What kind if treatments could interfere with the basic mechanisms of cell dysfunction and disease progression over time to delay, stop or reverse tissue dysfunction?
Submitted by Healthcare Professional x 1 
PSP information
PSP unique ID 0095
PSP name Mitochondrial Disease
Total number of uncertainties identified by this PSP. 42  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 19 January 2020