Medically Not Yet Explained Symptoms

Medically Not Yet Explained Symptoms represent up to 10-30% of presentations in general medicine settings. They can include fatigue, pain, dizziness, irritable bowel syndrome, and functional neurological symptoms.  

The focus of research on Medically Not Yet Explained Symptoms is often on particular subsets of symptoms, such as chronic pain, chronic fatigue, irritable bowel syndrome, or dizziness, but it lacks a comprehensive view.  This has ramifications for patients who visit different clinics for their various symptoms, without sustained improvement.

The Medically Not Yet Explained Symptoms PSP was established in 2020 to support patients, carers and clinicians in the UK and in the Netherlands in the development of a research agenda with patient knowledge, experience and preferences as the frame of reference. 

This Anglo-Dutch partnership also aimed to enable exploration of international and intercultural differences that might be of interest for future development of services and the co-design of research to develop better treatment and care.

The Medically Not Yet Explained Symptoms PSP UK Top 10 was published in September 2021.

 

Key documents

Medically Not Yet Explained Symptoms PSP Protocol

Medically Not Yet Explained Symptoms PSP Terms of Reference

Medically Not Yet Explained Symptoms PSP UK Engagement Summary

Medically Not Yet Explained Symptoms PSP UK Question Verification Form