Priority 10 from the Living With and Beyond Cancer PSP
|UNCERTAINTY: How can we predict which people living with and beyond cancer will experience long-term side-effects (side-effects which last for years after treatment) and which people will experience late effects (side-effects which do not appear until years after treatment)? (JLA PSP Priority 10)|
|JLA question ID||0073/10|
|Explanatory note||Not available for this PSP|
J Community Support Oncol. 2014 Apr;12(4):137-48. The late effects of cancer and cancer treatment: a rapid review. Treanor CJ1, Donnelly M.Myocardial infarction mortality risk after treatment for Hodgkin disease: a collaborative British cohort study.
Swerdlow AJ, Higgins CD, Smith P, Cunningham D, Hancock BW, Horwich A, Hoskin PJ, Lister A, Radford JA, Rohatiner AZ, Linch DC. J Natl Cancer Inst. 2007 Feb 7;99(3):206-14. Similar papers for breast ca for chemo and XRT SE
Macmillan document Shining the light on consequences of treatment which cites many references. We know that some treatments are associated risks of late effects. This depends on the disease, treatment and other factors
There are a lot of papers, reviews and evidence about late effects from cancer therapy in breast cancer and lymphoma/haem malignancies and childhood cancer but maybe not in every adult cancer.
Cancer treatment and survivorship statistics, 2016. K Miller et al. American Cancer Society Vol 66(4), 271-289.
|Health Research Classification System category||Cancer|
|Extra information provided by this PSP|
|Original uncertainty examples||The side effect left by cancer treatment like arthritis & lympheodema ~ What are the common long term effects of treatments when you have been cured of cancer? ~ Is neuropathy more common in bowel cancer with right ascending hemicolectomy, and if so how often is this linked to B12 deficiency? ~ What is the likelihood of lung problems following radiotherapy?|
|Submitted by||Individual survey submissions categorised by Healthcare professional, Patient, Relative/Carer, Other, and Unknown. For full details of the type of submitter for each individual question, please see the spreadsheet of data held on the JLA website.|
|PSP unique ID||0073|
|PSP name||Living With and Beyond Cancer|
|Total number of uncertainties identified by this PSP.||54 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)|
|Date of priority setting workshop||11 June 2018|