Priority 5 from the Hyperemesis Gravidarum PSP

UNCERTAINTY: What are the immediate and long term effects of hyperemesis gravidarum (including malunutrition and dehydration, stress) on the developing foetus?   (JLA PSP Priority 5)
Overall ranking 5
JLA question ID 0090/5
Explanatory note Not available for this PSP

Some immediate effects identified in systematic review but long term consequences require further study: Veenendaal MV, van Abeelen AF, Painter RC, van der Post JA, Roseboom TJ. Consequences of hyperemesis gravidarum for offspring: a systematic review and meta-analysis. Bjog. 2011;118(11):1302-13. 

Health Research Classification System category Reproductive health and childbirth
Extra information provided by this PSP
Original uncertainty examples What are the effects/consequences of HG for the baby and the mother in long term? ~ What are the risks to the fetus when a woman has Hyperemisis Gravidarum? ~ What are the long term effects of a HG pregnancy on the health of a child? (Impact of medication but also, is there any impact on the child anyway without meds e.g. long term growth, IQ, physical health, mental health etc)
Submitted by Patients x 112 ~ Healthcare professionals x 25 ~ Carers x 3 ~ Offspring x 8 ~ Organisational representatives x 1 ~ Unknown x 3 
PSP information
PSP unique ID 0090
PSP name Hyperemesis Gravidarum
Total number of uncertainties identified by this PSP. 65  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 9 October 2019