Priority 12 from the Hyperemesis Gravidarum PSP
|UNCERTAINTY: Why are some cases of hyperemesis gravidarum unresponsive to all antiemetics and how can we treat such cases? (JLA PSP Priority 12)
|JLA question ID
|Not available for this PSP
Cause of unresponsiveness not addressed in literature. Various novel therapies, enteral/parenteral feeding and termination proposed for unresponsive cases in a small number of papers and the two guidelines.
|Health Research Classification System category
|Reproductive health and childbirth
|Extra information provided by this PSP
|Original uncertainty examples
|Why in some cases is it not possible to control the sickness and vomiting? ~ Why doesn’t medication work (good enough)? ~ Why do different medications or combinations of medications work (or not work) for different patients? ~ Why don’t pills or medications work against the hg effects?
|Patients x 3
|PSP unique ID
|Total number of uncertainties identified by this PSP.
|65 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
|Date of priority setting workshop
|9 October 2019