Priority 10 from the Hip and Knee Replacement for Osteoarthritis PSP

UNCERTAINTY: What is the best way to protect patients from the risk of thrombotic (blood clots, bleeding) events associated with hip/knee replacement?  (JLA PSP Priority 10)
Overall ranking 10
JLA question ID 0020/10
Explanatory note Not available for this PSP
Evidence

Ongoing study: Tranexamic Acid vs. Quixil - Reducing Blood Loss in Joint Replacement ClinicalTrials.gov Identifier:
NCT00378872;
Health Research Classification System category Musculoskeletal
Extra information provided by this PSP
Original uncertainty examples Risk of clot post-operatively. Benefit of using the anti-DVT stockings? Difficulties putting on the compression stockings as patients cannot bend past 90 degrees at the hip post-op.  ~  blood clot, because obviously when you’re stationary that is a concern, especially post surgery  ~  There are huge cost implications and inconvenience for patients who have to wear surgical stockings and a massive demand on social services. Are the stockings really effective in the prevention of DVT following joint replacement.?  ~  How long do patients have to wear TED stockings after knee and hip replacement surgery
Submitted by Uncertainty identified by 2 clinicians,  and 2 from Healthtalk Online data
Outcomes to be measured Rick of thrombotic events
PSP information
PSP unique ID 0020
PSP name Hip and Knee Replacement for Osteoarthritis
Total number of uncertainties identified by this PSP. 123  (To see more about the Top 10, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 27 March 2014