Priority 14 from the Heart Surgery PSP

UNCERTAINTY: What are the best ways to prevent, diagnose and treat patients with acute aortic dissection (including long-term management)? (JLA PSP Priority 14)
Overall ranking 14
JLA question ID 0088/14
Explanatory note The European Guidelines on the diagnosis and treatment of aortic diseases identify a series of gap in current knowledge mostly related to aortic aneurysm and chronic dissection that can nonetheless be extended to aortic dissection.
~ Research into aortic dissection including diagnosis, management, new procedures is needed. What can we do to improve early diagnosis of aortic dissection? How can emergency treatment Aortic Dissection be improved? At what measurements should aortic repair be considered with aortic aneurysms?  
Evidence

Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC). Eur Heart J. 2014;35(41):2873-926; L. F. Hiratzka, G. L. Bakris, J. A. Beckman, R. M. Bersin, V. F. Carr, D. E. Casey, K. A. Eagle, L. K. Hermann, E. M. Isselbacher, E. A. Kazerooni, N. T. Kouchoukos, B. W. Lytle, D. M. Milewicz, D. L. Reich, S. Sen, J. A. Shinn, L. G. Svensson, D. M. Williams, G. American College of Cardiology Foundation/American Heart Association Task Force on Practice, S. American Association for Thoracic, R. American College of, A. American Stroke, A. Society of Cardiovascular, A. Society for Cardiovascular, Interventions, R. Society of Interventional, S. Society of Thoracic and M. Society for Vascular ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology,American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons,and Society for Vascular Medicine. 

Health Research Classification System category Cardiovascular
Extra information provided by this PSP
Original uncertainty examples Raising awareness - what can we do to improve early diagnosis of aortic dissection? ~ How to improve Aortic Dissection Emergency treatment? ~ At what measurements should aortic repair be considered with aortic aneurysms? ~ Research into aortic dissection, detection, aftercare, new procedures and improced outomes 
Submitted by 43 x patient, 11 x carer, 15 x healthcare professional
PSP information
PSP unique ID 0088
PSP name Heart Surgery
Total number of uncertainties identified by this PSP. 45  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 11 July 2019