Priority 1 from the Heart Surgery PSP

UNCERTAINTY: How does a patient quality of life (QOL) change (eg disability-free survival) due to heart surgery and what factors are associated with this?  (JLA PSP Priority 1)
Overall ranking 1
JLA question ID 0088/1
Explanatory note Quality of life (QOL) is a frequently assessed outcome in high quality scientific publications in cardiac surgery, often in those addressing issues related to rehabilitation.
Recent guidelines regard it as a necessary criteria to consider when making a recommendation, along with life expectancy. Nonetheless, most systematic reviews report insufficient data regarding this outcome.
~ Will QOL improve after heart surgery? Compare the QOL for patients undergoing on pump vs off pump CABG. What predicts poor outcome after cardiac surgery that impacts quality of life? 
Evidence

Anderson L, Taylor RS. Cardiac rehabilitation for people with heart disease: an overview of Cochrane systematic reviews. Cochrane Database of Systematic Reviews. 2014(12); Pogosova N, Saner H, Pedersen SS, Cupples ME, McGee H, Höfer S, et al. Psychosocial aspects in cardiac rehabilitation: From theory to practice. A position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation of the European Society of Cardiology. European journal of preventive cardiology. 2015;22(10):1290-306. 
Health Research Classification System category Cardiovascular
Extra information provided by this PSP
Original uncertainty examples How to improve quality of life? ~ What predicts poor outcome after cardiac surgery that impacts quality of life? ~ What interventions can improve disability-free survival in the longer term? 
Submitted by 1 x patient, 28 x healthcare professional
PSP information
PSP unique ID 0088
PSP name Heart Surgery
Total number of uncertainties identified by this PSP. 45  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 11 July 2019