Priority 26 from the Healthcare Associated Infections Project

UNCERTAINTY: Are single-day antibiotics better than longer course of antibiotics in treating urinary tract infection? (Priority 26)
Overall ranking 26
JLA question ID 0088/26
Explanatory note The optimal duration of treatment for urinary tract infections is not known. Traditionally, it has been considered that not taking the antibiotics for a certain number of days will result in incomplete eradication of infection. However, this might also mean that people continue to take antibiotics even after the eradication of infection. Shorter course of antibiotics can avoid this. However, the benefits and harms of such a short course of antibiotics is not known.

Systematic review: Goodlet et al. Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e02165-18.
Systematic review details:
This is a high risk of bias systematic review and the conclusions are unreliable

Health Research Classification System category Infection
Extra information provided by this project
Original uncertainty examples In urinary tract infections, is a single day of antibiotics as good as a longer course?
Submitted by 1 x Healthcare Professional
Project information
Project unique ID 0088
Project name Healthcare Associated Infections
Total number of uncertainties identified by this project. 259  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 28 February 2019