Priority 19 from the Healthcare Associated Infections Project

UNCERTAINTY: Does antibiotic prescription based on point-of-care (bedside) C-reactive protein to diagnose bacterial infection decrease amount of antibiotic prescription, antibiotic resistance, and hospital admission due to community-acquired pneumonia? (Priority 19)
Overall ranking 19
JLA question ID 0088/19
Explanatory note Prescribing antibiotics based on C-reactive protein (a substance in the body that is increased in the presence of inflammation or infection) may decrease the necessity and duration of antibiotics. However, there is significant uncertainty about the safety and effectiveness of such an approach.
Evidence

Only in children: Schot et al. NPJ Prim Care Respir Med. 2018 Oct 26;28(1):40.
Systematic review details:
More studies are necessary
Health Research Classification System category Infection
Extra information provided by this project
Original uncertainty examples Would point of care CRP testing in GP surgeries reduce antibiotic prescribing / hospital admission?
Submitted by  1 x Healthcare Professional
Project information
Project unique ID 0088
Project name Healthcare Associated Infections
Total number of uncertainties identified by this project. 259  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 28 February 2019