Priority 12 from the Healthcare Associated Infections Project

UNCERTAINTY: How does individualised antimicrobial dosing compare with standard dosing regimen in patients admitted in intensive care unit with infections? (Priority 12)
Overall ranking 12
JLA question ID 0088/12
Explanatory note Different individuals process the antibiotics differently. However, current regimens are based on average doses, which may either be too high or too low to treat the infection leading to increased complications or decreased effectiveness. There is uncertainty on how best to achieve this.
Evidence

None identified
Health Research Classification System category Infection
Extra information provided by this project
Original uncertainty examples In critical care infections, is individualised antimicrobial dosing more effective and safer than standard dosing
Submitted by  1 x Healthcare professional
Project information
Project unique ID 0088
Project name Healthcare Associated Infections
Total number of uncertainties identified by this project. 259  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 28 February 2019