Priority 5 from the COPD Exacerbation PSP

UNCERTAINTY: What are the associations between co-morbidity (other medical conditions) and risk of COPD exacerbations?  (JLA PSP Priority 5)
Overall ranking 5
JLA question ID 0104/5
Explanatory note People living with COPD often have other medical conditions too.  These are called 'co-morbidities'.  This question seeks to better understand the relationship between co-morbidities and exacerbations.  For example, is someone with anxiety and depression, or heart problems, likely to develop and/or experience exacerbations in a different way, that might lead to different outcomes or the need for different treatments? 

This question is an area of uncertainty.;;

Health Research Classification System category  Respiratory
Extra information provided by this PSP
Original uncertainty examples

Should we, and if so how can we reduce the risk of heart attack and stroke around the time of an exacerbation?~ Does dysphagia increase exacerbation risk? ~ Is there a role for SLT in preventing COPD exacerbations?~ Can controlling gastro-oesophageal reflux disease reduce the risk of copd exacerbation ~ does better management of cardiovascular disease reduce 'exacerbation' frequency  

Submitted by Patient, Healthcare professional 
PSP information
PSP unique ID 0104
PSP name COPD Exacerbation PSP
Total number of uncertainties identified by this PSP. 51 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 1 April 2021