Priority 15 from the COPD Exacerbation PSP

UNCERTAINTY: What factors determine whether someone with a COPD exacerbation can be managed at home or needs admission to hospital? (JLA PSP Priority 15)
Overall ranking 15
JLA question ID 0104/15
Explanatory note People with more severe COPD, or more severe exacerbations may need hospital care when they are unwell.  This question seeks to better understand which factors are important in deciding whether or not someone should be assessed at hospital when having an exacerbation, compared to being managed at home. 
Evidence

This is an area of uncertainty. 
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003573.pub2/full 

Health Research Classification System category  Respiratory
Extra information provided by this PSP
Original uncertainty examples

Best marker/symptom to guide home community care vs admission ~ Advice on Treatment at home rather than going to hospital ~ Should patients be treat at home with an exacerbation if they are given treatment & are safe to stay at home and have a community nurse to re-evaluate daily
Does home review by on-call community COPD nurse allow treatments at home? ~ Which treatments prevent readmission to hospital following COPD exacerbations? ~ Can we safely treat more patients in the community e..g. hospital at home setting?

Submitted by Patient, Healthcare professional
PSP information
PSP unique ID 0104
PSP name COPD Exacerbation PSP
Total number of uncertainties identified by this PSP. 51 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 1 April 2021