Priority 11 from the Cavernoma PSP

UNCERTAINTY: Is stereotactic radiosurgery or neurosurgery for brain or spine cavernomas better for improving outcome? (JLA PSP Priority 11)
Overall ranking 11
JLA question ID 0035/11
Explanatory note Not available for this PSP

Badhiwala J.H. Farrokhyar F. Alhazzani W. Yarascavitch B. Ed Aref M. Algird A, et al. Surgical outcomes and natural history of intramedullary spinal cord cavernous malformations: a single-center series and meta-analysis of individual patient data. Journal of Neurosurgery: Spine. 2014;21 (4):662-76. doi: 10.3171/2014.6.SPINE13949. Epub 2014 Jul 25.  Poorthuis M. Samarasekera N. Kontoh K. Stuart I. Cope B. Kitchen N. Al-Shahi Salman R. Comparative studies of the diagnosis and treatment of cerebral cavernous malformations in adults: Systematic review. Acta Neurochirurg. 2013;155 (4):643-9. doi: 10.1007/s00701-013-1621-4. Epub 2013 Jan 31.                                                                                         

Poorthuis MH, Klijn CJ, Algra A, Rinkel GJ, Al‐Shahi Salman R. Treatment of cerebral cavernous malformations: a systematic review and meta‐regression analysis. J Neurol Neurosurg Psychiatr. 2014; 85(12):1319-23. doi: 10.1136/jnnp-2013-307349. Epub 2014 Mar 25.   

Health Research Classification System category  Neurological
Extra information provided by this PSP
Original uncertainty examples Not available
Submitted by  
Outcomes to be measured  
PSP information
PSP unique ID 0035
PSP name Cavernoma
Total number of uncertainties identified by this PSP. 54  
Date of priority setting workshop 23 September 2015