Priority 6 from the Blood Transfusion and Blood Donation PSP

UNCERTAINTY: How can patients with anaemia be identified and treated in a timely manner so that the need for transfusion is avoided? (JLA PSP Priority 6)
Overall ranking 6
JLA question ID 0063/6
Explanatory note Not available for this PSP

1. Potter LJ, Doleman B, Moppett IK. A systematic review of pre-operative anaemia and blood transfusion in patients with fractured hips. Anaesthesia. 2015;70(4):483-500.
2. Ng O, Keeler BD, Mishra A, Simpson A, Neal K, Brookes MJ, et al. Iron therapy for pre-operative anaemia. Cochrane Database of Systematic Reviews. 2015(-12):CD011588-CD.
3. Hogan M, Klein AA, Richards T. The impact of anaemia and intravenous iron replacement therapy on outcomes in cardiac surgery. European Journal of Cardio-Thoracic Surgery. 2015;47(2):218-26.
4. Chan AW, de Gara CJ. An evidence-based approach to red blood cell transfusions in asymptomatically anaemic patients. Annals of the Royal College of Surgeons of England. 2015;97(-8):556-62.
5. Borstlap WA, Stellingwerf ME, Moolla Z, Musters GD, Buskens CJ, Tanis PJ, et al. Iron therapy for the treatment of preoperative anaemia in patients with colorectal carcinoma: a systematic review. Colorectal Disease. 2015;17(-12):1044-54.

Other Types:
1. Bonovas S, Fiorino G, Allocca M, Lytras T, Tsantes A, Peyrin-Biroulet L, et al. Intravenous versus oral iron for the treatment of anemia in inflammatory bowel disease: a systematic review and meta-analysis of randomized controlled trials. Medicine. 2016;95(-2):e2308-e.
2. Tay HS, Soiza RL. Systematic review and meta-analysis: what is the evidence for oral iron supplementation in treating anaemia in elderly people? Drugs & Aging. 2015;32(2):149-58.

Health Research Classification System category Generic Health Relevance
Extra information provided by this PSP
Original uncertainty examples Are patients being screened and treated for anaemia before surgery to prevent the need for blood transfusion? ~ How to promote early identification of patients who are anaemic who are going to need a transfusion and treat it to avoid them needing a transfusion? ~ Does a transfusion to correct anaemia lead to the true cause of the anaemia being missed? 
Submitted by 1 blood recipient ~ 4 relatives or carers of blood recipients ~ 6 blood donors ~ 8 health professionals ~ 1 unknown
PSP information
PSP unique ID 0063
PSP name Blood Transfusion and Blood Donation
Total number of uncertainties identified by this PSP 51  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 28 February 2018