Priority 16 from the Blood Transfusion and Blood Donation PSP

UNCERTAINTY: What characteristics identify patients who would benefit from a blood transfusion? (JLA PSP Priority 16)
Overall ranking 16
JLA question ID 0063/16
Explanatory note Not available for this PSP


Hunt H; Stanworth S; Curry N; Woolley T; Cooper C; UkoumunneO; Zhelev Z; Hyde C. Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma-induced coagulopathy in adult trauma patients with bleeding. Cochrane Database of Systematic Reviews. 2015;(2):CD010438
Health Research Classification System category Generic Health Relevance
Extra information provided by this PSP
Original uncertainty examples What is the benefit of blood transfusion in patients with evidence of poor oxygen delivery/organ dysfunction? ~ How well does donated blood carry oxygen in particular for patients with respiratory disease? ~ What should be the criteria for transfusion? ~ Blood products are given to a lot of patients who should possibly not be given one - need robust data to decide.  ~ What clinical markers should we use to show that patients have benefited from blood transfusion (particularly in preterm neonates)?
Submitted by 5 relatives or carers of blood recipients ~ 5 blood donors ~ 8 health professionals
PSP information
PSP unique ID 0063
PSP name Blood Transfusion and Blood Donation
Total number of uncertainties identified by this PSP 51  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 28 February 2018