Priority 20 from the Advanced Heart Failure PSP
|UNCERTAINTY: Do health professionals understand the life / activity / functional consequences of each medicine? (JLA PSP Priority 20)
|JLA question ID
No significant evidence for people with advanced heart failure
No systematic reviews on this topic in past five years
|Health Research Classification System category
|Extra information provided by this PSP
|Original uncertainty examples
|[My comments are around the huge consequences of one drug over another when both are in the same class. Specifically, how bisoprolol acted like a cosh whereas carvedilol was just pulled you down a little. There seemed to be little appreciation (or sympathy) for the difference in effect, and the life consequences. Being on Bisoprolol meant I couldn't walk 50 metres without sitting on a neighbour's wall with a heaving chest. Carvedilol meant I could cycle 5km to my cardiology appointment.] In sum the question is do clinicians really appreciate the life/activity/functional consequences of one medicine over another and the effects of titration of a given drug?
|1 x patient
|PSP unique ID
|Advanced Heart Failure
|Total number of uncertainties identified by this PSP.
|65 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
|Date of priority setting workshop
|13 February 2019