Priority 1 from the Revision Knee Replacement PSP

UNCERTAINTY: What are the causes of persistent pain following a knee replacement? How can the pain be prevented or minimised?  (JLA PSP Priority 1)
Overall ranking 1
JLA question ID 0093/1
Explanatory note Pain, which persists after the initial recovery period following knee replacements, remains one of the main of the biggest concern for patients and professionals alike. This topic ranked top in both groups throught out the process. In particular, participants want to better understand what can cause it and  what can be done to  prevent or minimise such pain. 
Evidence

 None identified
Health Research Classification System category Musculoskeletal
Extra information provided by this PSP
Original uncertainty examples Why does my friend's knee replacement still hurt/cause pain? ~ Are we able to identify surgical factors that may be relevant to painful TKRs? ~ Is there a common factor/factors in what causes pain and failure in knee replacement? ~ Why does my knee replacement that was supposed to last for 20 years, done in 2013, cause me pain? ~ How to improve inability to kneel on operated knee following TKR due to pain from tissues.
Submitted by See data spreadsheet on JLA website
PSP information
PSP unique ID 0093
PSP name Revision Knee Replacement
Total number of uncertainties identified by this PSP. 32  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 21 May 2019