Priority 1 from the Electronic Cigarettes PSP

UNCERTAINTY: What are the long term effects of vaping? Compared to smoking, ex-smokers, never-smokers and NRT use? (JLA PSP Priority 1)
Overall ranking 1
JLA question ID 0087/1
Explanatory note  Not available for this PSP
Evidence

More longitudinal studies are needed. Some people have been vaping for 10 years now, so it is possible to now look at the long-term effects. 
Health Research Classification System category  Generic health relevance
Extra information provided by this PSP
Original uncertainty examples

What are the long term effects of e-cigarette use? ~ long term harms to health with relative risk against non smoking and against tobacco"
Submitted by  57 x Healthcare professionals,  155 x Patients
PSP information
PSP unique ID 0087
PSP name Electronic Cigarettes
Total number of uncertainties identified by this PSP. 52 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 20 September 2019