The James Lind Alliance (JLA) is a non-profit making initiative which was established in 2004. It brings patients, carers and clinicians together in Priority Setting Partnerships (PSPs) to identify and prioritise the Top 10 uncertainties, or 'unanswered questions', about the effects of treatments that they agree are most important.

The aim of this is to help ensure that those who fund health research are aware of what matters to both patients and clinicians.
PSP Top tens

Top 10s

See the top priorities for future research, agreed by patients, carers and health professionals working with Priority Setting Partnerships.


About the JLA

The PSPs

Find out more about the areas in which Priority Setting Partnerships have been identifying the uncertainties which really matter.


The JLA guidebook


Read a step-by-step guide to the processes involved in a Priority Setting Partnership. Essential for achieving a useful outcome.


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JLA works with NIHR