Priority from the Teenage and Young Adult Cancer PSP

UNCERTAINTY: What is the best treatment for brain cancers to increase survival and decrease toxicity?
Overall ranking This was one of the 20 questions at the workshop that fell outside of the Top 10. These were not ranked in any order of priority
JLA question ID 0060/24
Explanatory note There are some very specific short and long term effects from therapies for those with a brain tumour, which can have a big impact on how young people get to live their lives, for example, in terms of employment, and the 'job' they can do as opposed to what they wanted to do. More clinical trials, that consider quality of life and survival, are required. 
Evidence

None identified
Health Research Classification System category Cancer
Extra information provided by this PSP
Original uncertainty examples What is the best treatment protocol for relapsed mixed germ cell brain tumour ~  What is the recommended protocol for re-irradiation of the brain ? ~ Why can we not find better and safer ways for treating brain tumours without causing damage to young people? ~ What treatments will cure aninoperable  brain tumour? ~ Is there a better way to deliver chemotherapy to brain tumours?  
Submitted by 6 parent/carers ~ 1 x partners
PSP information
PSP unique ID 0060
PSP name Teenage and Young Adult Cancer
Total number of uncertainties identified by this PSP. 185  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 19 January 2018