Priority 1 Sight Loss and Vision PSP Cataract

UNCERTAINTY: How can we prevent cataracts from developing? (JLA PSP Priority 1)
Overall ranking 1
JLA question ID 0014b/1
Explanatory note Reliable up-to-date systematic reviews revealed important continuing uncertainties about treatment effects at the time of the PSP
Evidence Mathew MC, Ervin AM, Tao J, Davis RM. Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract. Cochrane Database of Systematic Reviews 2012, Issue 6. Art. No.: CD004567. DOI: 10.1002/14651858.CD004567.pub2.
Health Research Classification System category Eye
Extra information provided by this PSP
Original uncertainty examples This is an indicative uncertainty and was submitted 18 times and the following submissions were merged to form this uncertainty: Can we prevent the development of cataract? How can cataracts be prevented from progressing, or eliminated altogether? How can we prevent cataracts from developing? How can we prevent or delay the onset of cataract formation? How can we prevent people from developing cataract? Is there anything that can be done to delay or prevent the onset of cataract formation? What can we do to avoid suffering from cataract? What can we do to avoid the formation of cataracts? What can we do to reduce the risk of developing cataracts? What can we do to avoid suffering from cataract?
Systematic reviews in preparation (at the time of PSP) Dubois VDJP, Bastawrous A. N-acetylcarnosine (NAC) drops for age-related cataract (Protocol). Cochrane Database of Systematic Reviews 2011, Issue 12. Art. No.: CD009493. DOI: 10.1002/14651858.CD009493
Ongoing controlled trials None identified
Submitted by Patients
Outcomes to be measured Incidence of cataract;adverse effects or complications; acceptability to patients or carers;health related quality of life; and costs
PSP information
PSP unique ID 0014b
PSP name Sight Loss and Vision - Cataract
Total number of uncertainties identified by this PSP. 42  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop April and May 2013