Priority 7 from the Multiple Sclerosis PSP

UNCERTAINTY: Which treatments are effective to improve mobility for people with multiple sclerosis? (JLA PSP Priority 7)
Overall ranking 7
JLA question ID 0016/7
Explanatory note Existing relevant systematic reviews are not up-to-date
Evidence

No evidence found
Systematic reviews that need extending or updating

Katalinic OM, Harvey LA, Herbert RD, Moseley AM, Lannin NA, Schurr K. Stretch for the treatment and prevention of contractures. Cochrane Database of Systematic Reviews 2010, Issue 9. Art. No.: CD007455. DOI: 10.1002/14651858.CD007455.pub2.
Systematic reviews in preparation

Prabhu RKR, Swaminathan N, Harvey LA. Passive movements for the treatment and prevention of contractures (Protocol). Cochrane Database of Systematic Reviews 2011, Issue 9. Art. No.: CD009331. DOI: 10.1002/14651858.CD009331.
Ongoing controlled trials

A trial to compare the effectiveness of two rehabilitation programs for Multiple Sclerosis patients REHABMUSCLE NCT01871818

Study on the evaluation of hippotherapy in the course of treatment for multiple sclerosis http://www.drks.de/DRKS00005289 Home Exercise Intervention in Persons With Multiple Sclerosis HOMS NCT01824550
Health Research Classification System category Neurological
Extra information provided by this PSP
Original uncertainty examples No examples provided.  This is an indicative uncertainty and several submissions were merged to form this one. 
Submitted by 6 patients
Outcomes to be measured Management and or change of multiple sclerosis symptoms; adverse effects or complications; acceptability to patients or carers; time to return to work or normal activity; time in hospital and or needing health or social care services; health related quality of life; and costs.
PSP information
PSP unique ID 0016
PSP name Multiple Sclerosis
Total number of uncertainties identified by this PSP. 82  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop July 2013