Priority 3 from the Miscarriage PSP

UNCERTAINTY: What investigations are of true clinical value? (e.g. ultrasound, gene sequencing, natural killer cells, thromboelastography (TEG),  microarray testing of the fetus, paternal investigations, plasminogen activator inhibitor polymorphism) (JLA PSP Priority 3)
Overall ranking 3
JLA question ID 0053/3
Explanatory note Examples of original survey submissions: Could the risk of miscarriage be identified earlier using biological markers, either in early pregnancy or pre-conception?; Usefulness of plasminogen activator inhibitor 4G/5G polymorphism testing in recurrent miscarriage ; Further research on testing of expelled tissue?; Why the fathers are not investigated to see if there is a cause for repeated miscarriage 
Evidence

None identified
Health Research Classification System category Reproduction
Extra information provided by this PSP
Submitted by 10 professionals ~ 44 women
PSP information
PSP unique ID 0053
PSP name Miscarriage
Total number of uncertainties identified by this PSP. 58  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 14 October 2016