Priority 16 from the Mesothelioma PSP

UNCERTAINTY: Should treatment for mesothelioma, if the patient has no symptoms, be given immediately or delayed? (JLA PSP Priority 16)
Overall ranking 16
JLA question ID 0025/16 
Explanatory note Not available for this PSP
Evidence Ongoing study - A multicentre non-blinded randomised controlled trial to assess the impact of Regular Early SPEcialist symptom Control Treatment on quality of life in malignant Mesothelioma - “RESPECT-Meso”
Health Research Classification System category Cancer
Extra information provided by this PSP
Original uncertainty examples Would like to see trial of early vs delayed treatments in asymptomatic/minimally symptomatic pts repeated. There was a 50:50 split last time I saw it debated - which implies we really don't know the best answer ~ Chemotherapy was the only treatment on offer (though not needed as yet)
Comparison Drug
Submitted by Health Professional ~ Patient
Outcomes to be measured Survival and Quality of Life
PSP information
PSP unique ID 0025
PSP name Mesothelioma
Total number of uncertainties identified by this PSP. 53  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 16 December 2014