Priority 13 from the Kidney Transplant PSP

UNCERTAINTY: How can we increase the number of potential living donors coming forward, and the proportion proceeding to donation?
Overall ranking Priority questions agreed on but not put in ranked order
JLA question ID 0037/13
Explanatory note Not available for this PSP
Evidence

Existing Systematic Reviews: Hanson, C., Chadban, S. J., Chapman, J. R., Craig, J. C., Wong, G., Ralph, A. F., Tong, A. The expectations and attitudes of patients with chronic kidney disease toward living kidney donor transplantation: a thematic synthesis of qualitative studies. Transplantation. 2015;99(3):540-54
Existing Randomised Controlled Trials: Rodrigue, J. R. ; Cornell, D. L. ; Kaplan, B. A randomized trial of a home-based educational approach to increase live donor kidney transplantation: effects in blacks and whites. Am J Kidney Dis. 2008 Apr;51(4):663-70. doi: 10.1053/j.ajkd.2007.11.027. Epub 2008 Mar 4. PMID: 18371542 ~
Barnieh, L ; McLaughlin, K ; Manns, B J. ; Klarenbach, S. ; Yilmaz, S. ; Taub, K. ; Hemmelgarn, B R. Evaluation of an education intervention to increase the pursuit of living kidney donation: a randomized controlled trial. Progress in Transplantation. 2011;21(1):36-42 PMID: 21485941 ~
Increasing Live Donor Kidney Transplantation: A Randomized Controlled Trial of a Home-Based Educational Intervention
Rodrigue, J. R. ; Cornell, D. L. ;  Lin, J. K. ; Kaplan, B. ; Howard, R. J.
American Journal of Transplantation. 2007;7(2):394-401 PMID: 17173659 ~
Home-based family intervention increases knowledge, communication and living donation rates: a randomized controlled trial.
Ismail SY, Luchtenburg AE, Timman R, Zuidema WC, Boonstra C, Weimar W, Busschbach JJ, Massey EK. Am J Transplant. 2014 Aug;14(8):1862-9. doi: 10.1111/ajt.12751. Epub 2014 Jun 16.  PMID: 24935081
Ongoing Randomised Controlled Trials: Your path to transplant: a randomized controlled trial of a tailored computer education intervention to increase living donor kidney transplant. BMC Nephrology. 2014;15(1):166
PMID: 25315644; NCT02181114 ~
Weng FL, Brown DR, Peipert JD, Holland B, Waterman AD. Protocol of a cluster randomized trial of an educational intervention to increase knowledge of living donor kidney transplant among potential transplant candidates. BMC Nephrology. 2013;14:256. doi:10.1186/1471-2369-14-256
Health Research Classification System category Renal and Urogenital
Extra information provided by this PSP
Original uncertainty examples

Why is live kidney donation not promoted? For those considering living kidney donation, what are the main impediments to going through with the donation? Can the process of putting themselves forward for donation be made clearer for living donors, especially when there is more than one potential donor? How many people in the general population are aware you don't have to be related to a recipient to donate a kidney? Why is the rate of living donor transplantation low in asian patients As a living donor (16 Oct 13), I found that the actual offer of one of my kidneys to my brother was one of the hardest things I have ever done.  I also think that he (and his wife) found asking the family quite difficult.  Why is there not a process whereby the transplant centre asks people instead of the recipient asking?

If this was done, the recipient could simply provide a long list of e-mails for potential donors, who would all receive a suitable e-mail from the transplant centre, and then they could ask questions etc BEFO
Comparison Education and training
Submitted by

Patients x 6 Clinicians x 1
Outcomes to be measured Number of potential donors, proportion proceeding to donation.
PSP information
PSP unique ID 0037
PSP name Kidney Transplant
Total number of uncertainties identified by this PSP. 90  (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 3 February 2016