Priority from the Bleeding Disorders PSP

UNCERTAINTY: What is the impact of the gut microbiome on immune thrombocytopenic purpura (ITP))? 
Overall ranking This was one of the 15 questions at the workshop that fell outside of the Top 10. These were not ranked in any order of priority
JLA question ID 0078/13
Explanatory note The blood protein profile is dominated by products from the gut microbiome. There is mounting evidence that this has an important influence on disease.  Understanding the specific role in ITP may open up new treatments. 
Evidence No systematic reviews identified
Health Research Classification System category Blood
Extra information provided by this PSP
Original uncertainty examples Not available
Submitted by Not available
PSP information
PSP unique ID 0078
PSP name Bleeding Disorders
Total number of uncertainties identified by this PSP. 66 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 7 July 2018