Priority 8 from the Alcohol-related Liver Disease PSP

UNCERTAINTY: What interventions improve survival in individuals with complications of advanced alcohol-related cirrhosis? (JLA PSP Priority 8)
Overall ranking 8
JLA question ID 0044/8
Explanatory note (including examples of original survey submissions) This question largely relates to the use of steroids. "How can we identify which patients with severe alcoholic hepatitis benefit from steroids?"  "What is the optimal duration of steroid therapy in severe alcoholic hepatitis (assuming initial response by Lille criteria)?"  "How can you predict if someone will respond to a treatment or not?"
Evidence Protocol for a systematic review: Thorley H; Porter K; Fleming C; Jones T; Kesten J; Marques E; et al. Interventions for preventing or treating malnutrition in problem drinkers who are homeless or vulnerably housed: protocol for a systematic review. Systems Review. 2014:4;131.
Health Research Classification System category Oral and Gastrointestinnal
Extra information provided by this PSP
Submitted by 21 Professionals
PSP information
PSP unique ID 0044
PSP name Alcohol-related Liver Disease
Total number of uncertainties identified by this PSP. 45 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop 16 September 2016